USS Voyager comes across a damaged Hirogen space craft and sends an away team to investigate. They return back to the Voyager with an injured Hirogen survivor. The survivor reveals he has been tracking an alien life form that is not native to this part of the universe. When Harry Kim discovers anomalies in engineering, they discover an injured Species 8472 who had been unabled to return his universe. The Species wants to return back to fluidic space.
Captain Kathryn Janeway orders Seven of Nine to help but the ex-Borg declines because of what the creature did to her Borg friends. When Hirogen space craft turn up en masse and demand both prey and hunter, Janeway refuses however Seven teleports both hunter and prey to a Hirogen craft and the Hirogen fleet leave.